2016年10月16日星期日

为什么要进行药物浓度检测?Why we do medicine concentration test?


任何药物都具有两重性,既能治病,也能致病。传统的给药方法是参照药物说书推荐的剂量给药,但因存在个体差异,相同的给药剂量在不同的个体间会有不同药物浓度。对那些药物安全浓度范围窄的药物而言,传统的经验用药可能会导致仅有一部分患者得到应有的疗效,而部分患者因药物浓度过低而未能达到预期的疗效,部分患者可能因药物深度过高而出现毒性作用。近年来在肾脏病治疗上取得较好疗效的多种免疫抑制类药物如环孢霉素、他克莫司(普乐可复)、雷帕霉素(西罗莫司)等都属于该类药物,无论剂量高低都可能出现不良反应。为了使药物达到最佳的疗效和最低的毒副作用,必须以检测各自血液中的药物浓度为依据,来调整用药方案,以得到好的疗效。
我们的优势:石家庄肾病医院采用国际先进的微粒子化学发光法,配以美国Abbott ARCHITECT i1000SR全自动免疫分析仪,经过多年检测,技术成熟,结果准确快速。
Duality, any drug can cure, also can cause disease.The traditional dosing method is reference to the dose of drug storyteller recommended, but due to individual differences, the same dose between different individuals have different drug concentrations.For those drugs with narrow safe concentration range, the experience of the traditional drug use may result in only part of patients get  curative effect, and some patients because drug concentration is too low and failed to achieve the desired effect and toxicity of some patients may appear because the depth of the drug was too high. Immunosuppressive drugs Obtained the good curative effect in the treatment of kidney disease in recent years such as cyclosporine, tacrolimus (zyprexa compound), rapamycin (sirolimus) belong to this kind of drugs, both high and low doses might have adverse reactions.In order to make the drug to achieve the best curative effect and the minimum side effects, must be based on detection of each drug concentration in blood, to adjust the regimen, in order to get good curative effect.
Our advantage: shijiazhuang kidney disease hospital adopts international advanced micro particle chemiluminescence method, matching with the Abbott ARCHITECT i1000SR automatic immunity analyzer, after many years of testing, mature technology, results fast and accurate.

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