2016年10月16日星期日

1.PLA2R(判断是否为膜性肾病) PLA2R (membranous nephropathy)


PLA2R(抗磷脂酶A2受体抗体)检测的作用:膜性肾病是导致成人肾病综合征的一个常见病因。西方国家膜性肾病约占原发性肾小球肾炎的30%,近年来国内报道膜性肾病发病率逐渐升高。膜性肾病起病往往较隐匿,以往主要依靠病理学诊断,对患者压力大,且与疾病的严重性或疗效无关。2009年膜性肾病的自身免疫学机制被发现,抗PLA2R成为特发性膜性肾病的特异性诊断指标,特异性高达特异性为98%100%,且具有less,费用低,同时对患者压力小等优点。血清抗PLA2R的滴度的升高、减少或消失等结果可评估临床情况以及治疗措施是否成功。
我们的优势:石家庄肾病医院从2013年起应用德国欧蒙欧蒙生物技术有限公司试剂在国内较早的开展了抗PLA2R检测,经过大量的样本检测,技术成熟,结果准确可靠,对特发性膜性肾病的诊断起到了很好的作用。

Function of PLA2R: membranous is a common reason of causing to adult nephrotic syndrome. Membranous disease in western occupied 30% in primary glomerular nephritis. Onset of membranous often is latent, it was diagnosed by pathology, patient had high pressure and it has no matter with illness condition severity and curative effects. Immunological mechanisms of membranous was found in 2009, anti-PLA2R became the specificity of diagnostic indicators of Idiopathic membranous nephropathy, its specificity is as high as 98%-100%, it has the advantage of less time consuming, low cost and little pressure. Titer of blood serum anti-PLA2Rs increasing, decreasing or disappear can assess clinical condition and whether treatment measures success or not.
Our advantage: Shijiazhuang Kidney Disease Hospital apply to anti-PLA2R earlier, through amounts of tests on samples, its skills are experienced, the result is more accurate, has a good function for diagnosing membranous nephropathy.

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