PTH(甲状旁腺激素)1-84 PTH (parathyroid hormone). 1-84

慢性肾脏病-矿物质和骨异常是由于慢性肾脏病导致的矿物质及骨代谢异常综合征，是慢性肾脏病最常见的并发病之一。甲状旁腺激素是评估慢性肾脏病-矿物质和骨异常的重要指标之一。甲状旁腺激素是一种含84个氨基酸的多肽激素，在血循环中以四种形式存在：全段PTH(1-84 PTH)、氨基端片段PTH、中间段PTH及羧基端片段PTH，后二者无生物学活性。PTH检测的主要困难在于片段PTH的存在，尤其是在CKD患者中，片段PTH的存在使不同的PTH检测方法出现不同的结果。
目前常用的全段PTH(iPTH)检测时际上包含1-84 PTH和7-84 PTH两种片段，而7-84 PTH的存在使检测结果并不准确。
我们的优势：石家庄肾病医院采用德国罗氏第三代PTH检测技术检测真正的1-84氨基酸全长PTH分子。比iPTH检测值有更加准确的临床应用。CHOICE研究发现，1-84 PTH升高和透析患者死亡率增加有关，而iPTH则无统计学意义。


Chronic kidney disease-mineral and bone abnormality is due to mineral and bone metabolism syndrome of chronic kidney disease , which is one of the most common complications of chronic kidney disease. Parathyroid hormone is evaluation of chronic kidney disease (CKD) - one of the important indexes of mineral and bone abnormalities. Parathyroid hormone is a kind of containing 84 amino acid polypeptide hormones in the blood circulation exist in four forms: segment PTH (1-84 (PTH), amino end segment PTH, the middle period of PTH and carboxyl end pieces PTH, after the two no biological activities.PTH testing the main segments of the difficulty is that the existence of PTH, especially in patients with chronic kidney disease (CKD), fragments of PTH exist different PTH detection method appeared different results.
At present commonly used the entire section of PTH (iPTH) detection in the containing PTH and 7-1-84 84 PTH two fragments, and the existence of 7-84 PTH testing results are not accurate.

Our advantage: shijiazhuang kidney disease hospital adopts Germany roche's third generation of PTH detecting technology in real 1-84 amino acid molecules span PTH.Are more accurate than iPTH values in clinical application.CHOICE, the study found elevated PTH and 1-84 dialysis patients is associated with increased mortality, and iPTH, no statistical signifi